Semiconducting polymer nano-PROTACs for activatable photo-immunometabolic cancer therapy

Immunometabolic intervention has been applied to treat cancer via inhibition of certain enzymes associated with intratumoral metabolism. However, small-molecule inhibitors and genetic modification often suffer from insufficiency and off-target side effects. Proteolysis targeting chimeras (PROTACs) p...

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Udgivet i:Nat Commun
Main Authors: Zhang, Chi, Zeng, Ziling, Cui, Dong, He, Shasha, Jiang, Yuyan, Li, Jingchao, Huang, Jiaguo, Pu, Kanyi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8131624/
https://ncbi.nlm.nih.gov/pubmed/34006860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23194-w
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