Functional and structural characterization of a two-MAb cocktail for delayed treatment of enterovirus D68 infections

Enterovirus D68 (EV-D68) is an emerging pathogen associated with respiratory diseases and/or acute flaccid myelitis. Here, two MAbs, 2H12 and 8F12, raised against EV-D68 virus-like particle (VLP), show distinct preference in binding VLP and virion and in neutralizing different EV-D68 strains. A comb...

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Udgivet i:Nat Commun
Main Authors: Zhang, Chao, Xu, Cong, Dai, Wenlong, Wang, Yifan, Liu, Zhi, Zhang, Xueyang, Wang, Xuesong, Wang, Haikun, Gong, Sitang, Cong, Yao, Huang, Zhong
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8131599/
https://ncbi.nlm.nih.gov/pubmed/34006855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23199-5
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