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Integrated transcriptomics and epigenomics reveal chamber-specific and species-specific characteristics of human and mouse hearts

DNA methylation, chromatin accessibility, and gene expression represent different levels information in biological process, but a comprehensive multiomics analysis of the mammalian heart is lacking. Here, we applied nucleosome occupancy and methylome sequencing, which detected DNA methylation and ch...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Gao, Junpeng, Zheng, Yuxuan, Li, Lin, Lu, Minjie, Chen, Xiangjian, Wang, Yu, Li, Yanna, Liu, Xiaomeng, Gao, Yun, Mao, Yunuo, Zhao, Peng, Zhang, Jinan, Tang, Fuchou, Song, Lei, Wen, Lu, Wang, Jizheng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8130971/
https://ncbi.nlm.nih.gov/pubmed/34003819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3001229
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