Metabolic Reprogramming of GMP Grade Cord Tissue Derived Mesenchymal Stem Cells Enhances Their Suppressive Potential in GVHD

Acute graft-vs.-host (GVHD) disease remains a common complication of allogeneic stem cell transplantation with very poor outcomes once the disease becomes steroid refractory. Mesenchymal stem cells (MSCs) represent a promising therapeutic approach for the treatment of GVHD, but so far this strategy...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Mendt, Mayela, Daher, May, Basar, Rafet, Shanley, Mayra, Kumar, Bijender, Wei Inng, Francesca Lim, Acharya, Sunil, Shaim, Hila, Fowlkes, Natalie, Tran, Jamie P., Gokdemir, Elif, Uprety, Nadima, Nunez-Cortes, Ana K., Ensley, Emily, Mai, Thao, Kerbauy, Lucila N., Melo-Garcia, Luciana, Lin, Paul, Shen, Yifei, Mohanty, Vakul, Lu, JunJun, Li, Sufang, Nandivada, Vandana, Wang, Jing, Banerjee, Pinaki, Reyes-Silva, Francia, Liu, Enli, Ang, Sonny, Gilbert, April, Li, Ye, Wan, Xinhai, Gu, Jun, Zhao, Ming, Baran, Natalia, Muniz-Feliciano, Luis, Wilson, Jeffrey, Kaur, Indreshpal, Gagea, Mihai, Konopleva, Marina, Marin, David, Tang, Guilin, Chen, Ken, Champlin, Richard, Rezvani, Katayoun, Shpall, Elizabeth J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8130860/
https://ncbi.nlm.nih.gov/pubmed/34017325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.631353
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