Factor IX assay discrepancies in the setting of liver gene therapy using a hyperfunctional variant factor IX‐Padua

BACKGROUND: Limited information exists regarding the factor IX (FIX) coagulant activity (FIX:C) measured by different assays following FIX‐Padua gene therapy. OBJECTIVE: Assess for the first time FIX:C in five commonly used coagulation assays in plasma samples from hemophilia B subjects receiving FI...

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Dettagli Bibliografici
Pubblicato in:J Thromb Haemost
Autori principali: Robinson, Mary M., George, Lindsey A., Carr, Marcus E., Samelson‐Jones, Benjamin J., Arruda, Valder R., Murphy, John E., Rybin, Denis, Rupon, Jeremy, High, Katherine A., Tiefenbacher, Stefan
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2021
Soggetti:
HAEMOSTASIS
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8130854/
https://ncbi.nlm.nih.gov/pubmed/33636038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.15281
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