Main protease inhibitors and drug surface hotspots for the treatment of COVID-19: A drug repurposing and molecular docking approach

Here, drug repurposing and molecular docking were employed to screen approved MPP inhibitors and their derivatives to suggest a specific therapeutic agent for the treatment of COVID-19. The approved MPP inhibitors against HIV and HCV were prioritized, while RNA dependent RNA Polymerase (RdRp) inhibi...

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Enregistré dans:
Détails bibliographiques
Publié dans:Biomed Pharmacother
Auteurs principaux: Hasan, Mahmudul, Parvez, Md. Sorwer Alam, Azim, Kazi Faizul, Imran, Md. Abdus Shukur, Raihan, Topu, Gulshan, Airin, Muhit, Samuel, Akhand, Rubaiat Nazneen, Ahmed, Syed Sayeem Uddin, Uddin, Md Bashir
Format: Artigo
Langue:Inglês
Publié: Published by Elsevier Masson SAS. 2021
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8130501/
https://ncbi.nlm.nih.gov/pubmed/34052565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopha.2021.111742
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