Immunotherapy for the prevention of high-risk oral disorders malignant transformation: the IMPEDE trial

BACKGROUND: Oral Potentially Malignant Disorders (OPMD) have a non-negligible malignant transformation rate of up to 8%. Loss of heterozygosity (LOH) in critical chromosomal loci has proven to be the most effective marker in defining the risk of transformation and it is found in about 28% of OPMD an...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Gurizzan, Cristina, Lorini, Luigi, Paderno, Alberto, Tomasoni, Michele, Zigliani, Gabriele, Bozzola, Anna, Ardighieri, Laura, Battocchio, Simonetta, Bignotti, Eliana, Ravaggi, Antonella, Romani, Chiara, De Cecco, Loris, Serafini, Mara Serena, Miceli, Rosalba, Bardellini, Elena, Majorana, Alessandra, Piazza, Cesare, Bossi, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Study Protocol
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8130439/
https://ncbi.nlm.nih.gov/pubmed/34001010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-021-08297-3
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