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mTOR controls endoplasmic reticulum–Golgi apparatus trafficking of VSVg in specific cell types

BACKGROUND: Mammalian/mechanistic target of rapamycin (mTOR) complexes are essential for cell proliferation, growth, differentiation, and survival. mTORC1 hyperactivation occurs in the tuberous sclerosis complex (TSC). mTORC1 localizes to the surface of lysosomes, where Rheb activates it. However, m...

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Detalhes bibliográficos
Publicado no:Cell Mol Biol Lett
Main Authors: Koscielny, Alicja, Liszewska, Ewa, Machnicka, Katarzyna, Wezyk, Michalina, Kotulska, Katarzyna, Jaworski, Jacek
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8130434/
https://ncbi.nlm.nih.gov/pubmed/34006213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s11658-021-00262-z
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