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Neurohormonal activation induces intracellular iron deficiency and mitochondrial dysfunction in cardiac cells

BACKGROUND: Iron deficiency (ID) is common in patients with heart failure (HF) and is associated with poor outcomes, yet its role in the pathophysiology of HF is not well-defined. We sought to determine the consequences of HF neurohormonal activation in iron homeostasis and mitochondrial function in...

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Publicat a:Cell Biosci
Autors principals: Tajes, M., Díez-López, C., Enjuanes, C., Moliner, P., Ferreiro, J. L., Garay, A., Jiménez-Marrero, S., Yun, S., Sosa, S. G., Alcoberro, L., González-Costello, J., García-Romero, E., Yañez-Bisbe, L., Benito, B., Comín-Colet, J.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8130332/
https://ncbi.nlm.nih.gov/pubmed/34001233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-021-00605-5
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