Worenine reverses the Warburg effect and inhibits colon cancer cell growth by negatively regulating HIF-1α

BACKGROUND: Some natural compounds inhibit cancer cell growth in various cancer cell lines with fewer side effects than traditional chemotherapy. Here, we explore the pharmacological effects and mechanisms of worenine (isolated from Coptis chinensis) against colorectal cancer. METHODS: The effects o...

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Detalhes bibliográficos
Publicado no:Cell Mol Biol Lett
Main Authors: Ji, Lijiang, Shen, Weixing, Zhang, Feng, Qian, Jie, Jiang, Jie, Weng, Liping, Tan, Jiani, Li, Liu, Chen, Yugen, Cheng, Haibo, Sun, Dongdong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research Letter
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8130299/
https://ncbi.nlm.nih.gov/pubmed/34006215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s11658-021-00263-y
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