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PD-1-inhibitor pembrolizumab for treatment of progressive multifocal leukoencephalopathy

The reactivation of human JC polyoma virus (JCPyV) results in lytic infection of oligodendrocytes and neuronal cells. The corresponding clinical picture is called progressive multifocal leukoencephalopathy (PML) and results mostly from a disease-related or drug-induced immunosuppression. The opportu...

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Detalhes bibliográficos
Publicado no:Ther Adv Neurol Disord
Main Authors: Möhn, Nora, Wattjes, Mike P., Adams, Ortwin, Nay, Sandra, Tkachenko, Daria, Salge, Friederike, Heine, Johanne, Pars, Kaweh, Höglinger, Günter, Respondek, Gesine, Stangel, Martin, Skripuletz, Thomas, Jacobs, Roland, Sühs, Kurt-Wolfram
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8129640/
https://ncbi.nlm.nih.gov/pubmed/34035834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1756286421993684
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