The neutrotime transcriptional signature defines a single continuum of neutrophils across biological compartments

Neutrophils are implicated in multiple homeostatic and pathological processes, but whether functional diversity requires discrete neutrophil subsets is not known. Here, we apply single-cell RNA sequencing to neutrophils from normal and inflamed mouse tissues. Whereas conventional clustering yields m...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Grieshaber-Bouyer, Ricardo, Radtke, Felix A., Cunin, Pierre, Stifano, Giuseppina, Levescot, Anaïs, Vijaykumar, Brinda, Nelson-Maney, Nathan, Blaustein, Rachel B., Monach, Paul A., Nigrovic, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8129206/
https://ncbi.nlm.nih.gov/pubmed/34001893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22973-9
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