Toxoplasma LIPIN is essential in channeling host lipid fluxes through membrane biogenesis and lipid storage

Apicomplexa are obligate intracellular parasites responsible for major human diseases. Their intracellular survival relies on intense lipid synthesis, which fuels membrane biogenesis. Parasite lipids are generated as an essential combination of fatty acids scavenged from the host and de novo synthes...

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Vydáno v:Nat Commun
Hlavní autoři: Dass, Sheena, Shunmugam, Serena, Berry, Laurence, Arnold, Christophe-Sebastien, Katris, Nicholas J., Duley, Samuel, Pierrel, Fabien, Cesbron-Delauw, Marie-France, Yamaryo-Botté, Yoshiki, Botté, Cyrille Y.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8129101/
https://ncbi.nlm.nih.gov/pubmed/34001876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22956-w
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