OPA1 deletion in brown adipose tissue improves thermoregulation and systemic metabolism via FGF21

Adrenergic stimulation of brown adipocytes alters mitochondrial dynamics, including the mitochondrial fusion protein optic atrophy 1 (OPA1). However, direct mechanisms linking OPA1 to brown adipose tissue (BAT) physiology are incompletely understood. We utilized a mouse model of selective OPA1 delet...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:eLife
Main Authors: Pereira, Renata O, Marti, Alex, Olvera, Angela Crystal, Tadinada, Satya Murthy, Bjorkman, Sarah Hartwick, Weatherford, Eric Thomas, Morgan, Donald A, Westphal, Michael, Patel, Pooja H, Kirby, Ana Karina, Hewezi, Rana, Bùi Trân, William, García-Peña, Luis Miguel, Souvenir, Rhonda A, Mittal, Monika, Adams, Christopher M, Rahmouni, Kamal, Potthoff, Matthew J, Abel, E Dale
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2021
Assuntos:
Biochemistry and Chemical Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8128440/
https://ncbi.nlm.nih.gov/pubmed/33944779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.66519
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados