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PTBP1 Targets ILK to Regulate the Hypoxia-Induced Phenotypic Transformation of Pulmonary Artery Smooth Muscle Cells

PURPOSE: Pulmonary hypertension (PH) is a pathological process mainly characterized by the progressive increase in pulmonary vascular resistance. The degradation of pulmonary artery smooth muscle cells (PASMCs) from contractile/differentiated phenotype to synthetic/dedifferentiated phenotype is a ke...

詳細記述

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書誌詳細
出版年:Drug Des Devel Ther
主要な著者: Yan, Gaoliang, Sun, Renhua, Chen, Zhongpu, Pan, Xiaodong, Sheng, Zulong, Tang, Chengchun
フォーマット: Artigo
言語:Inglês
出版事項: Dove 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8128346/
https://ncbi.nlm.nih.gov/pubmed/34012255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S275000
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