Deep immune profiling of MIS-C demonstrates marked but transient immune activation compared to adult and pediatric COVID-19

Pediatric COVID-19 following SARS-CoV-2 infection is associated with fewer hospitalizations and often milder disease than in adults. A subset of children, however, present with Multisystem Inflammatory Syndrome in Children (MIS-C) that can lead to vascular complications and shock, but rarely death....

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Detalhes bibliográficos
Publicado no:Sci Immunol
Main Authors: Vella, Laura A., Giles, Josephine R., Baxter, Amy E., Oldridge, Derek A., Diorio, Caroline, Kuri-Cervantes, Leticia, Alanio, Cécile, Pampena, M. Betina, Wu, Jennifer E., Chen, Zeyu, Huang, Yinghui Jane, Anderson, Elizabeth M., Gouma, Sigrid, McNerney, Kevin O., Chase, Julie, Burudpakdee, Chakkapong, Lee, Jessica H., Apostolidis, Sokratis A., Huang, Alexander C., Mathew, Divij, Kuthuru, Oliva, Goodwin, Eileen C., Weirick, Madison E., Bolton, Marcus J., Arevalo, Claudia P., Ramos, Andre, Jasen, CJ, Conrey, Peyton E, Sayed, Samir, Giannini, Heather M., D’Andrea, Kurt, Meyer, Nuala J., Behrens, Edward M., Bassiri, Hamid, Hensley, Scott E., Henrickson, Sarah E., Teachey, David T., Betts, Michael R., Wherry, E. John
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8128303/
https://ncbi.nlm.nih.gov/pubmed/33653907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.abf7570
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