Caricamento...
The complex role of SIRT7 in p53 stabilization: nucleophosmin joins the debate
Release of nucleophosmin (NPM) from nucleoli following stress promotes rapid stabilization of the tumor suppressor p53 (TP53, best known as p53). Nucleoplasmic NPM binds to the ubiquitin ligase mouse double minute 2 (MDM2) and prevents MDM2-dependent p53 degradation. We recently demonstrated that si...
Salvato in:
| Pubblicato in: | Mol Cell Oncol |
|---|---|
| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
2021
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8128210/ https://ncbi.nlm.nih.gov/pubmed/34027038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2021.1896349 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|