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Implications of ADAM17 activation for hyperglycaemia, obesity and type 2 diabetes

In this review, we focus specifically on the role that the metalloproteinase, A Disintegrin and Metalloproteinase 17 [ADAM17] plays in the development and progression of the metabolic syndrome. There is a well-recognised link between the ADAM17 substrate tumour necrosis factor α (TNF-α) and obesity,...

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Dettagli Bibliografici
Pubblicato in:Biosci Rep
Autori principali: Matthews, Jennifer, Villescas, Sofia, Herat, Lakshini, Schlaich, Markus, Matthews, Vance
Natura: Artigo
Lingua:Inglês
Pubblicazione: Portland Press Ltd. 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8128101/
https://ncbi.nlm.nih.gov/pubmed/33904577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20210029
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