Pan-cancer transcriptomic predictors of perineural invasion improve occult histopathological detection

PURPOSE: Perineural invasion (PNI) is associated with aggressive tumor behavior, recurrence, and metastasis, and can influence the administration of adjuvant treatment. However, standard histopathological examination has limited sensitivity in detecting PNI and does not provide insights into its mec...

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Publicat a:Clin Cancer Res
Autors principals: Guo, Jimmy A., Hoffman, Hannah I., Shroff, Stuti, Chen, Peter, Hwang, Peter G., Kim, Daniel Y., Kim, Daniel W., Cheng, Stephanie W., Zhao, Daniel, Mahal, Brandon A., Alshalalfa, Mohammed, Niemierko, Andrzej, Wo, Jennifer Y., Loeffler, Jay S., Castillo, Carlos Fernandez-del, Jacks, Tyler, Aguirre, Andrew J., Hong, Theodore S., Mino-Kenudson, Mari, Hwang, William L.
Format: Artigo
Idioma:Inglês
Publicat: 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8127360/
https://ncbi.nlm.nih.gov/pubmed/33632928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-20-4382
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