Design considerations of an IL13Rα2 antibody–drug conjugate for diffuse intrinsic pontine glioma

Diffuse intrinsic pontine glioma (DIPG), a rare pediatric brain tumor, afflicts approximately 350 new patients each year in the United States. DIPG is noted for its lethality, as fewer than 1% of patients survive to five years. Multiple clinical trials involving chemotherapy, radiotherapy, and/or ta...

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Опубликовано в: :Acta Neuropathol Commun
Главные авторы: Lian, Xiaolei, Kats, Dina, Rasmussen, Samuel, Martin, Leah R., Karki, Anju, Keller, Charles, Berlow, Noah E.
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2021
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8127302/
https://ncbi.nlm.nih.gov/pubmed/34001278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-021-01184-9
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