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The Wnt/β-Catenin Pathway Modulates Vascular Remodeling and Specification by Upregulating Dll4/Notch Signaling

The Wnt/β-catenin pathway is evolutionary conserved signaling system that regulates cell differentiation and organogenesis. We show that endothelial specific stabilization of Wnt/β-catenin signaling alters early vascular development in the embryo. The phenotype resembles that induced by upregulation...

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Foilsithe in:Dev Cell
Main Authors: Corada, Monica, Nyqvist, Daniel, Orsenigo, Fabrizio, Caprini, Andrea, Giampietro, Costanza, Taketo, Makoto M., Iruela-Arispe, M. Luisa, Adams, Ralf H., Dejana, Elisabetta
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8127076/
https://ncbi.nlm.nih.gov/pubmed/20627076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2010.05.006
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