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Pharmacological restoration of anti-nociceptive functions in the prefrontal cortex relieves chronic pain

Chronic pain affects one in four adults, and effective non-sedating and non-addictive treatments are urgently needed. Chronic pain causes maladaptive changes in the cerebral cortex, which can lead to impaired endogenous nociceptive processing. However, it is not yet clear if drugs that restore endog...

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Detalhes bibliográficos
Publicado no:Prog Neurobiol
Main Authors: Talay, Robert S, Liu, Yaling, Michael, Matthew, Li, Anna, Friesner, Isabel D, Zeng, Fei, Sun, Guanghao, Chen, Zhe Sage, Zhang, Qiaosheng, Wang, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8126990/
https://ncbi.nlm.nih.gov/pubmed/33545233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pneurobio.2021.102001
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