Centrosome‐mediated microtubule remodeling during axon formation in human iPSC‐derived neurons

Axon formation critically relies on local microtubule remodeling and marks the first step in establishing neuronal polarity. However, the function of the microtubule‐organizing centrosomes during the onset of axon formation is still under debate. Here, we demonstrate that centrosomes play an essenti...

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Detaylı Bibliyografya
Yayımlandı:EMBO J
Asıl Yazarlar: Lindhout, Feline W, Portegies, Sybren, Kooistra, Robbelien, Herstel, Lotte J, Stucchi, Riccardo, Hummel, Jessica J A, Scheefhals, Nicky, Katrukha, Eugene A, Altelaar, Maarten, MacGillavry, Harold D, Wierenga, Corette J, Hoogenraad, Casper C
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2021
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8126955/
https://ncbi.nlm.nih.gov/pubmed/33835529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020106798
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