Centrosome‐mediated microtubule remodeling during axon formation in human iPSC‐derived neurons

Axon formation critically relies on local microtubule remodeling and marks the first step in establishing neuronal polarity. However, the function of the microtubule‐organizing centrosomes during the onset of axon formation is still under debate. Here, we demonstrate that centrosomes play an essenti...

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Bibliografische gegevens
Gepubliceerd in:EMBO J
Hoofdauteurs: Lindhout, Feline W, Portegies, Sybren, Kooistra, Robbelien, Herstel, Lotte J, Stucchi, Riccardo, Hummel, Jessica J A, Scheefhals, Nicky, Katrukha, Eugene A, Altelaar, Maarten, MacGillavry, Harold D, Wierenga, Corette J, Hoogenraad, Casper C
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2021
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Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8126955/
https://ncbi.nlm.nih.gov/pubmed/33835529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020106798
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