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Scaffold diversity for enhanced activity of glycosylated inhibitors of fungal adhesion

Candida albicans is one of the most prevalent fungal pathogens involved in hospital acquired infections. It binds to glycans at the surface of epithelial cells and initiates infection. This process can be blocked by synthetic carbohydrates that mimic the structure of cell surface glycans. Herein we...

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Библиографические подробности
Опубликовано в: :RSC Med Chem
Главные авторы: Martin, Harlei, Somers, Tara, Dwyer, Mathew, Robson, Ryan, Pfeffer, Frederick M., Bjornsson, Ragnar, Krämer, Tobias, Kavanagh, Kevin, Velasco-Torrijos, Trinidad
Формат: Artigo
Язык:Inglês
Опубликовано: RSC 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8126883/
https://ncbi.nlm.nih.gov/pubmed/34095846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0md00224k
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