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The aryl hydrocarbon receptor suppresses immunity to oral squamous cell carcinoma through immune checkpoint regulation

Immune checkpoint inhibitors represent some of the most important cancer treatments developed in the last 20 y. However, existing immunotherapy approaches benefit only a minority of patients. Here, we provide evidence that the aryl hydrocarbon receptor (AhR) is a central player in the regulation of...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Kenison, Jessica E., Wang, Zhongyan, Yang, Kangkang, Snyder, Megan, Quintana, Francisco J., Sherr, David H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8126867/
https://ncbi.nlm.nih.gov/pubmed/33941684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2012692118
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