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The aryl hydrocarbon receptor suppresses immunity to oral squamous cell carcinoma through immune checkpoint regulation

Immune checkpoint inhibitors represent some of the most important cancer treatments developed in the last 20 y. However, existing immunotherapy approaches benefit only a minority of patients. Here, we provide evidence that the aryl hydrocarbon receptor (AhR) is a central player in the regulation of...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Kenison, Jessica E., Wang, Zhongyan, Yang, Kangkang, Snyder, Megan, Quintana, Francisco J., Sherr, David H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8126867/
https://ncbi.nlm.nih.gov/pubmed/33941684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2012692118
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