Membrane fusion and drug delivery with carbon nanotube porins

Drug delivery mitigates toxic side effects and poor pharmacokinetics of life-saving therapeutics and enhances treatment efficacy. However, direct cytoplasmic delivery of drugs and vaccines into cells has remained out of reach. We find that liposomes studded with 0.8-nm-wide carbon nanotube porins (C...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Ho, Nga T., Siggel, Marc, Camacho, Karen V., Bhaskara, Ramachandra M., Hicks, Jacqueline M., Yao, Yun-Chiao, Zhang, Yuliang, Köfinger, Jürgen, Hummer, Gerhard, Noy, Aleksandr
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2021
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8126853/
https://ncbi.nlm.nih.gov/pubmed/33941689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2016974118
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