The voltage sensor is responsible for ΔpH dependence in H(v)1 channels

The dissipation of acute acid loads by the voltage-gated proton channel (H(v)1) relies on regulating the channel’s open probability by the voltage and the ΔpH across the membrane (ΔpH = pH(ex) − pH(in)). Using monomeric Ciona-H(v)1, we asked whether ΔpH-dependent gating is produced during the voltag...

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發表在:Proc Natl Acad Sci U S A
Main Authors: Carmona, Emerson M., Fernandez, Miguel, Alvear-Arias, Juan J., Neely, Alan, Larsson, H. Peter, Alvarez, Osvaldo, Garate, Jose Antonio, Latorre, Ramon, Gonzalez, Carlos
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2021
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8126849/
https://ncbi.nlm.nih.gov/pubmed/33941706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2025556118
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