Targeted systemic dendrimer delivery of CSF‐1R inhibitor to tumor‐associated macrophages improves outcomes in orthotopic glioblastoma

Glioblastoma is the most common and aggressive form of primary brain cancer, with median survival of 16–20 months and a 5‐year survival rates of <5%. Recent advances in immunotherapies have shown that addressing the tumor immune profile by targeting the colony‐stimulating factor 1 (CSF‐1) signali...

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Bibliographic Details
Published in:Bioeng Transl Med
Main Authors: Liaw, Kevin, Reddy, Rajsekhar, Sharma, Anjali, Li, Jiangyu, Chang, Michelle, Sharma, Rishi, Salazar, Sebastian, Kannan, Sujatha, Kannan, Rangaramanujam M.
Format: Artigo
Language:Inglês
Published: John Wiley & Sons, Inc. 2020
Subjects:
Research Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8126814/
https://ncbi.nlm.nih.gov/pubmed/34027092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/btm2.10205
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