Efficacy and Safety of Apatinib Treatment for Advanced Cholangiocarcinoma After Failed Gemcitabine-Based Chemotherapy: An Open-Label Phase II Prospective Study

PURPOSE: As a novel small-molecule vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor (VEGFR2-TKI), Methylsulfonic apatinib (apatinib) exhibits a specific antitumor effect in various solid tumors via inhibition of angiogenesis. The present study was performed to evaluate the cli...

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Udgivet i:Front Oncol
Main Authors: Zhang, Ge, Gong, Shuai, Pang, Lina, Hou, Lixia, He, Wei
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Oncology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8126718/
https://ncbi.nlm.nih.gov/pubmed/34012920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.659217
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