Case Report: Convalescent Plasma Achieves SARS-CoV-2 Viral Clearance in a Patient With Persistently High Viral Replication Over 8 Weeks Due to Severe Combined Immunodeficiency (SCID) and Graft Failure

We describe the unique disease course and cure of SARS-CoV-2 infection in a patient with SCID and graft failure. In absence of a humoral immune response, viral clearance was only achieved after transfusion of convalescent plasma. This observation underscores the necessity of the humoral immune respo...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Keitel, Verena, Bode, Johannes Georg, Feldt, Torsten, Walker, Andreas, Müller, Lisa, Kunstein, Anselm, Klindt, Caroline, Killer, Alexander, Senff, Tina, Timm, Jörg, Ostermann, Philipp, Damagnez, Maximilian, Lübke, Nadine, Adams, Ortwin, Schaal, Heiner, Antoch, Gerald, Neubert, Jennifer, Albrecht, Philipp, Meuth, Sven, Elben, Saskia, Mohring, Annemarie, Fischer, Johannes C., Bölke, Edwin, Hoenig, Manfred, Schulz, Ansgar S., Luedde, Tom, Jensen, Björn
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8126709/
https://ncbi.nlm.nih.gov/pubmed/34012436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.645989
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