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Protein kinase CK2: a potential therapeutic target for diverse human diseases

CK2 is a constitutively active Ser/Thr protein kinase, which phosphorylates hundreds of substrates, controls several signaling pathways, and is implicated in a plethora of human diseases. Its best documented role is in cancer, where it regulates practically all malignant hallmarks. Other well-known...

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Detalhes bibliográficos
Publicado no:Signal Transduct Target Ther
Main Authors: Borgo, Christian, D’Amore, Claudio, Sarno, Stefania, Salvi, Mauro, Ruzzene, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8126563/
https://ncbi.nlm.nih.gov/pubmed/33994545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41392-021-00567-7
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