The effect of targeting Tie2 on hemorrhagic shock-induced renal perfusion disturbances in rats

BACKGROUND: Hemorrhagic shock is associated with acute kidney injury and increased mortality. Targeting the endothelial angiopoietin/Tie2 system, which regulates endothelial permeability, previously reduced hemorrhagic shock-induced vascular leakage. We hypothesized that as a consequence of vascular...

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Dettagli Bibliografici
Pubblicato in:Intensive Care Med Exp
Autori principali: van Leeuwen, Anoek L. I., Dekker, Nicole A. M., Van Slyke, Paul, de Groot, Esther, Vervloet, Marc G., Roelofs, Joris J. T. H., van Meurs, Matijs, van den Brom, Charissa E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer International Publishing 2021
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8126531/
https://ncbi.nlm.nih.gov/pubmed/33997943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40635-021-00389-5
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