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The effect of targeting Tie2 on hemorrhagic shock-induced renal perfusion disturbances in rats

BACKGROUND: Hemorrhagic shock is associated with acute kidney injury and increased mortality. Targeting the endothelial angiopoietin/Tie2 system, which regulates endothelial permeability, previously reduced hemorrhagic shock-induced vascular leakage. We hypothesized that as a consequence of vascular...

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Detalhes bibliográficos
Publicado no:Intensive Care Med Exp
Main Authors: van Leeuwen, Anoek L. I., Dekker, Nicole A. M., Van Slyke, Paul, de Groot, Esther, Vervloet, Marc G., Roelofs, Joris J. T. H., van Meurs, Matijs, van den Brom, Charissa E.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8126531/
https://ncbi.nlm.nih.gov/pubmed/33997943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40635-021-00389-5
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