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Differences in RNA and microRNA Expression Between PTCH1- and SUFU-mutated Medulloblastoma
Background/Aim: Germline mutations in PTCH1 or SUFU in the sonic hedgehog (SHH) pathway cause Gorlin’s syndrome with increased risk of developing SHH-subgroup medulloblastoma. Gorlin’s syndrome precludes the use of radiotherapy (a standard component of treatment) due to the development of multiple b...
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| Publicado en: | Cancer Genomics Proteomics |
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| Autores principales: | , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
International Institute of Anticancer Research
2021
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8126327/ https://ncbi.nlm.nih.gov/pubmed/33893086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21873/cgp.20264 |
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