Differences in RNA and microRNA Expression Between PTCH1- and SUFU-mutated Medulloblastoma

Background/Aim: Germline mutations in PTCH1 or SUFU in the sonic hedgehog (SHH) pathway cause Gorlin’s syndrome with increased risk of developing SHH-subgroup medulloblastoma. Gorlin’s syndrome precludes the use of radiotherapy (a standard component of treatment) due to the development of multiple b...

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Publicat a:Cancer Genomics Proteomics
Autors principals: GERSHANOV, SIVAN, TOLEDANO, HELEN, PERNICONE, NOMI, FICHMAN, SUZANA, MICHOWIZ, SHALOM, PINHASOV, ALBERT, GOLDENBERG-COHEN, NITZA, LISTOVSKY, TAMAR, SALMON-DIVON, MALI
Format: Artigo
Idioma:Inglês
Publicat: International Institute of Anticancer Research 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8126327/
https://ncbi.nlm.nih.gov/pubmed/33893086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21873/cgp.20264
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