SUL-151 Decreases Airway Neutrophilia as a Prophylactic and Therapeutic Treatment in Mice after Cigarette Smoke Exposure

Chronic obstructive pulmonary disease (COPD) caused by cigarette smoke (CS) is featured by oxidative stress and chronic inflammation. Due to the poor efficacy of standard glucocorticoid therapy, new treatments are required. Here, we investigated whether the novel compound SUL-151 with mitoprotective...

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Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Wang, Lei, Pelgrim, Charlotte E., Swart, Daniël H., Krenning, Guido, van der Graaf, Adrianus C., Kraneveld, Aletta D., Leusink-Muis, Thea, van Ark, Ingrid, Garssen, Johan, Folkerts, Gert, Braber, Saskia
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8125869/
https://ncbi.nlm.nih.gov/pubmed/34066693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22094991
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