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Design and Development of D‒α‒Tocopheryl Polyethylene Glycol Succinate‒block‒Poly(ε-Caprolactone) (TPGS−b−PCL) Nanocarriers for Solubilization and Controlled Release of Paclitaxel

The objective of this study was to synthesize and characterize a set of biodegradable block copolymers based on TPGS-block-poly(ε-caprolactone) (TPGS-b-PCL) and to assess their self-assembled structures as a nanodelivery system for paclitaxel (PAX). The conjugation of PCL to TPGS was hypothesized to...

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Bibliografiske detaljer
Udgivet i:Molecules
Main Authors: Yusuf, Osman, Ali, Raisuddin, Alomrani, Abdullah H., Alshamsan, Aws, Alshememry, Abdullah K., Almalik, Abdulaziz M., Lavasanifar, Afsaneh, Binkhathlan, Ziyad
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8125698/
https://ncbi.nlm.nih.gov/pubmed/34064416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26092690
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