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Inhibition of Lipid Accumulation and Cyclooxygenase-2 Expression in Differentiating 3T3-L1 Preadipocytes by Pazopanib, a Multikinase Inhibitor

Pazopanib is a multikinase inhibitor with anti-tumor activity. As of now, the anti-obesity effect and mode of action of pazopanib are unknown. In this study, we investigated the effects of pazopanib on lipid accumulation, lipolysis, and expression of inflammatory cyclooxygenase (COX)-2 in differenti...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Yadav, Anil Kumar, Jang, Byeong-Churl
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8125232/
https://ncbi.nlm.nih.gov/pubmed/34063048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22094884
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