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Effects of Thrombomodulin in Reducing Lethality and Suppressing Neutrophil Extracellular Trap Formation in the Lungs and Liver in a Lipopolysaccharide-Induced Murine Septic Shock Model

Neutrophil extracellular trap (NET) formation, an innate immune system response, is associated with thrombogenesis and vascular endothelial injury. Circulatory disorders due to microvascular thrombogenesis are one of the principal causes of organ damage. NET formation in organs contributes to the ex...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Kato, Yu, Nishida, Osamu, Kuriyama, Naohide, Nakamura, Tomoyuki, Kawaji, Takahiro, Onouchi, Takanori, Hasegawa, Daisuke, Shimomura, Yasuyo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8124404/
https://ncbi.nlm.nih.gov/pubmed/34066510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22094933
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