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Evaluation of the PSMA-Binding Ligand (212)Pb-NG001 in Multicellular Tumour Spheroid and Mouse Models of Prostate Cancer

Radioligand therapy targeting the prostate-specific membrane antigen (PSMA) is rapidly evolving as a promising treatment for metastatic castration-resistant prostate cancer. The PSMA-targeting ligand p-SCN-Bn-TCMC-PSMA (NG001) labelled with (212)Pb efficiently targets PSMA-positive cells in vitro an...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Stenberg, Vilde Yuli, Larsen, Roy Hartvig, Ma, Li-Wei, Peng, Qian, Juzenas, Petras, Bruland, Øyvind Sverre, Juzeniene, Asta
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8124365/
https://ncbi.nlm.nih.gov/pubmed/34062920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22094815
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