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Targeting BTK Signaling in the Microenvironment of Solid Tumors as a Feasible Cancer Therapy Option

SIMPLE SUMMARY: Protein tyrosine kinase BTK is essential for B cell maturation and proliferation. Dysregulation of BTK signaling in B cells leads to B cell lymphoma. In addition to B cells, BTK is also expressed in other types of immune cells including MDSC, dendritic cells, mast cells and macrophag...

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Publicat a:Cancers (Basel)
Autors principals: Messex, Justin K., Liou, Geou-Yarh
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8124209/
https://ncbi.nlm.nih.gov/pubmed/34063667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13092198
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