Beraprost ameliorates postmenopausal osteoporosis by regulating Nedd4-induced Runx2 ubiquitination

Bone health requires adequate bone mass, which is maintained by a critical balance between bone resorption and formation. In our study, we identified beraprost as a pivotal regulator of bone formation and resorption. The administration of beraprost promoted differentiation of mouse bone mesenchymal...

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Udgivet i:Cell Death Dis
Main Authors: Zheng, Huo-Liang, Xu, Wen-Ning, Zhou, Wen-Sheng, Yang, Run-Ze, Chen, Peng-Bo, Liu, Tao, Jiang, Lei-Sheng, Jiang, Sheng-Dan
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8124066/
https://ncbi.nlm.nih.gov/pubmed/33993186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03784-8
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