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Effect of GLUT1 Inhibition and Autophagy Modulation on the Growth and Migration of Laryngeal Carcinoma Stem Cells Under Hypoxic and Low-Glucose Conditions

BACKGROUND: Enhanced glucose uptake and autophagy are means by which cells adapt to stressful microenvironments. In this study, we investigated the roles of glucose transporter-1 (GLUT-1) and autophagy in laryngeal carcinoma stem cells under hypoxic and low-glucose conditions. MATERIALS AND METHODS:...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Chen, Xiao-Hong, Liu, Jia, Zhong, Jiang-Tao, Zhou, Shui-Hong, Fan, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8124017/
https://ncbi.nlm.nih.gov/pubmed/34007184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S300423
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