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Combined Inhibition of TGF-β1-Induced EMT and PD-L1 Silencing Re-Sensitizes Hepatocellular Carcinoma to Sorafenib Treatment

Hepatocellular carcinoma (HCC) is the most common type of primary hepatic malignancy. HCC is one of the leading causes of cancer deaths worldwide. The oral multi-tyrosine kinase inhibitor Sorafenib is the standard first-line therapy in patients with advanced unresectable HCC. Despite the significant...

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Detalhes bibliográficos
Publicado no:J Clin Med
Main Authors: Shrestha, Ritu, Prithviraj, Prashanth, Bridle, Kim R., Crawford, Darrell H. G., Jayachandran, Aparna
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8123871/
https://ncbi.nlm.nih.gov/pubmed/33925488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm10091889
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