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NEIL1 and NEIL2 Are Recruited as Potential Backup for OGG1 upon OGG1 Depletion or Inhibition by TH5487

DNA damage caused by reactive oxygen species may result in genetic mutations or cell death. Base excision repair (BER) is the major pathway that repairs DNA oxidative damage in order to maintain genomic integrity. In mammals, eleven DNA glycosylases have been reported to initiate BER, where each rec...

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Bibliografski detalji
Izdano u:Int J Mol Sci
Glavni autori: Hanna, Bishoy M. F., Michel, Maurice, Helleday, Thomas, Mortusewicz, Oliver
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8123590/
https://ncbi.nlm.nih.gov/pubmed/33925271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22094542
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