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Overexpression of Isl1 under the Pax2 Promoter, Leads to Impaired Sound Processing and Increased Inhibition in the Inferior Colliculus

The LIM homeodomain transcription factor ISL1 is essential for the different aspects of neuronal development and maintenance. In order to study the role of ISL1 in the auditory system, we generated a transgenic mouse (Tg) expressing Isl1 under the Pax2 promoter control. We previously reported a prog...

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Dettagli Bibliografici
Pubblicato in:Int J Mol Sci
Autori principali: Chumak, Tetyana, Tothova, Diana, Filova, Iva, Bures, Zbynek, Popelar, Jiri, Pavlinkova, Gabriela, Syka, Josef
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8123449/
https://ncbi.nlm.nih.gov/pubmed/33925933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22094507
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