TLR4-Mediated Recognition of Mouse Polyomavirus Promotes Cancer-Associated Fibroblast-Like Phenotype and Cell Invasiveness

SIMPLE SUMMARY: Mouse polyomavirus (MPyV) is widely used as a model for cancer development studies. In many preceding studies, its tumorigenic potential was attributed to a virus protein called middle T antigen (MT), which possesses a transforming ability through activation of cell-associated tyrosi...

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Published in:Cancers (Basel)
Main Authors: Janovec, Vaclav, Ryabchenko, Boris, Škarková, Aneta, Pokorná, Karolína, Rösel, Daniel, Brábek, Jan, Weber, Jan, Forstová, Jitka, Hirsch, Ivan, Huérfano, Sandra
Format: Artigo
Language:Inglês
Published: MDPI 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8123340/
https://ncbi.nlm.nih.gov/pubmed/33923020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13092076
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