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Mechanisms of High-Grade Serous Carcinogenesis in the Fallopian Tube and Ovary: Current Hypotheses, Etiologic Factors, and Molecular Alterations

Ovarian high-grade serous carcinomas (HGSCs) are a heterogeneous group of diseases. They include fallopian-tube-epithelium (FTE)-derived and ovarian-surface-epithelium (OSE)-derived tumors. The risk/protective factors suggest that the etiology of HGSCs is multifactorial. Inflammation caused by ovula...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Autor principal: Otsuka, Isao
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8122889/
https://ncbi.nlm.nih.gov/pubmed/33922503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22094409
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