Inhibition of the Histone Methyltransferase EZH2 Enhances Protumor Monocyte Recruitment in Human Mesothelioma Spheroids

Malignant pleural mesothelioma (MPM) is a highly aggressive cancer with a long latency period and dismal prognosis. Recently, tazemetostat (EPZ-6438), an inhibitor of the histone methyltransferase EZH2, has entered clinical trials due to the antiproliferative effects reported on MPM cells. However,...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Mola, Silvia, Pinton, Giulia, Erreni, Marco, Corazzari, Marco, De Andrea, Marco, Grolla, Ambra A., Martini, Veronica, Moro, Laura, Porta, Chiara
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8122808/
https://ncbi.nlm.nih.gov/pubmed/33922336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22094391
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