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The Role of NRF2/KEAP1 Signaling Pathway in Cancer Metabolism

The nuclear factor-erythroid 2 p45-related factor 2 (NRF2, also called Nfe2l2) and its cytoplasmic repressor, Kelch-like ECH-associated protein 1 (KEAP1), are major regulators of redox homeostasis controlling a multiple of genes for detoxification and cytoprotective enzymes. The NRF2/KEAP1 pathway i...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Song, Moon-Young, Lee, Da-Young, Chun, Kyung-Soo, Kim, Eun-Hee
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8122702/
https://ncbi.nlm.nih.gov/pubmed/33922165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22094376
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