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Connectivity Map Analysis of a Single-Cell RNA-Sequencing -Derived Transcriptional Signature of mTOR Signaling

In the connectivity map (CMap) approach to drug repositioning and development, transcriptional signature of disease is constructed by differential gene expression analysis between the diseased tissue or cells and the control. The negative correlation between the transcriptional disease signature and...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Al Mahi, Naim, Zhang, Erik Y., Sherman, Susan, Yu, Jane J., Medvedovic, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8122562/
https://ncbi.nlm.nih.gov/pubmed/33922083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22094371
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