Loss of IL-33 enhances elastase-induced and cigarette smoke extract-induced emphysema in mice

BACKGROUND: IL-33, which is known to induce type 2 immune responses via group 2 innate lymphoid cells, has been reported to contribute to neutrophilic airway inflammation in chronic obstructive pulmonary disease. However, its role in the pathogenesis of emphysema remains unclear. METHODS: We determi...

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Gepubliceerd in:Respir Res
Hoofdauteurs: Morichika, Daisuke, Taniguchi, Akihiko, Oda, Naohiro, Fujii, Utako, Senoo, Satoru, Itano, Junko, Kanehiro, Arihiko, Kitaguchi, Yoshiaki, Yasuo, Masanori, Hanaoka, Masayuki, Satoh, Takashi, Akira, Shizuo, Kiura, Katsuyuki, Maeda, Yoshinobu, Miyahara, Nobuaki
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2021
Onderwerpen:
Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8122555/
https://ncbi.nlm.nih.gov/pubmed/33992109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-021-01705-z
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